Original Post
I'm going to have to go with Resident Evil - the one where Michelle Rodriguez says "poor bastard" at the woman in the tank in the first half of the movie (before they've shut the computer down) and as soon as she walks out of the frame, the camera zooms in, the music dissipates and suddenly the woman's eyes open an her hand is very abruptly on the glass. While I am not a big fan of Anderson's work in general, I think he did a well above average job with Resident Evil (even though I enjoyed Romero's original script - I believe I happened to read the final draft - a lot more than Anderson's, which made it into principal photography). Pulling off a shocker after basically spelling it out to the viewer that "a shocker is coming - get ready - aight, any time now" is somewhat of an art and there's actually several of those moments in Resident Evil. Still, the one I described above, is, in my opinion, easily the best. Your turn.